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Table 2 Primary outcome: changes within groups and differences between groups at month 24 (M24) in the proportion of patients achieving all their therapeutic targets

From: Effects of a multifaceted intervention on cardiovascular risk factors in high-risk hypertensive patients: the ESCAPE trial, a pragmatic cluster randomized trial in general practice

Endpoint

Group

M0 n/N (%)

M24 n/N (%)

OR (95% CI) for within group comparison

P

OR (95% CI) for between group comparison

P-value

All patients (3 or 5 targets)

Intervention

56/900 (6.2)

110/860 (12.8)

3.23 (2.12 to 4.94)

< 0.001

1.89 (1.09 to 3.27)

0.024

Usual care

94/923 (10.2)

118/860 (13.7)

1.71 (1.19 to 2.47)

0.004

Hypertension + T2D (5 targets)

Intervention

7/527 (1.3)

24/526 (4.6)

3.90 (1.60 to 9.52)

0.003

2.36 (0.68 to 8.18)

0.175

Usual care

9/520 (1.7)

14/513 (2.7)

1.65 (0.69 to 3.98)

0.262

Hypertension (3 targets)

Intervention

49/373 (13.1)

86/334 (25.8)

3.12 (1.94 to 5.03)

< 0.001

1.63 (0.99 to 3.01)

0.120

 

Usual care

85/403 (21.1)

104/347 (29.0)

1.91 (1.27 to 2.88)

0.002

  
  1. CI, confidence interval; M 0, month 0; M24, month 24; T2D, type-2 diabetes; OR, odds-ratio.