Inclusion criteria: | Â |
1. | Stable coronary heart disease with CCS functional classification of angina class I to III |
2. | Low self-rated physical activity |
3. | Condition after percutaneous coronary intervention > 4Â weeks until < 26Â weeks or > 52Â weeks after index percutaneous coronary intervention |
4. | Residence < 50Â km radius of the study center (city of Mainz) |
5. | If treatment with beta blockers or ivabradine then stable > 4Â weeks |
Exclusion criteria: | Â |
1. | Acute coronary syndrome or myocardial infarction < 8Â weeks |
2. | Coronary stenosis of the dominant vessel > 25% or high grade stenosis of the left coronary artery |
3. | Heart failure with left ventricular ejection fraction < 40% |
4. | NYHA III to IV |
5. | Severe heart valve disorder |
6. | Insulin dependent diabetes |
7. | Orthopedic or other disorders, which preclude regular physical activity |
8. | Coronary artery bypass surgery < 6Â months before index PCI |
9. | Severe obesity (BMI ≥ 40) |
10. | Need for systemic immunosuppression with cortisone or methotrexate |
11. | Kidney failure with need for dialysis |
12. | Intake of nitrates < 12Â hours |