LT4 -supplemented | Placebo | Difference (95% CI) LT4 - placebo | P value | |
---|---|---|---|---|
Subarachnoid space width at 36 weeks’ CGA (cm) | 0.20 (0.06) | 0.21 (0.062 | −0.01 (−0.03, 0.01) | 0.34 |
n=61 | n=57 | |||
Head circumference at 36 weeks’ CGA (cm) | 30.40 (1.90) | 30.61 (2.23) | −0.2 (−0.96, 0.54) | 0.49 |
n=61 | n=57 | |||
Leg length at 36 weeks’ CGA (mm) | 61.52 (8.90) | 65.20 (7.11) | −3.80 (−6.91, -0.62) | 0.02 |
n=53 | n=53 | |||
Mid arm circumference at 36 weeks’ CGA (mm) | 8.03 (1.07) | 8.19 (1.18) | −0.15 (−0.57, 0.25) | 0.47 |
n=60 | n=57 | |||
Weight at 36 weeks’ CGA (kg) | 1.90 (0.40) | 2.03 (0.40) | −0.11 (−0.26, 0.04) | 0.14 |
n=61 | n=57 | |||
Thyroid volume (mL) at 36 weeks’ CGA | 0.57 (0.17) | 0.57 (0.17) | 0.004 (−0.07, 0.06) | 0.99 |
n=59 | n=55 | |||
Mortality | 14 (18%) | 19 (24%) | −0.06(−0.19, 0.08) | 0.34 |
n=75 | n=78 | |||
Duration of mechanical ventilation (days) | 18.30 (13,38) | 21.00 (8,42) | −2.00 (−5.00, 8.00) | 0.56a |
n=58 | n=58 | |||
Days on total parenteral nutrition (TPN) | 14.00 (10,21) | 14.50 (11,21) | −1.00 (−4.00, 2.00) | 0.59a |
n=58 | n=58 | |||
Chronic lung disease (CLD) diagnosed | 42 (56%) | 39 (50%) | 0.06 (−0.10, 0.22) | 0.46 |
n=61 | n=57 | |||
Oxygen levels at 36 weeks’ CGA(L/min) for babies with CLD | 0.50 (0.08, 1.5) | 0.30 (0.08, 1.5) | 0.00 (−0.17, 0.20) | 0.99a |
n=61 | n=57 |