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Table 1 Demographics and baseline characteristics

From: An explanatory randomised placebo controlled trial of levothyroxine supplementation for babies born <28 weeks’ gestation: results of the TIPIT trial

 

LT4 -supplemented

Placebo

n= 75

n= 78

Gender (male)

44 (59%)

45 (58%)

Birth weight (grams)

820.7 (183.9)

842.2 (200.0)

Gestational age (weeks)

25.8 (1.3)

25.8 (1.4)

Clinical risk index for babies (CRIB) score

5.7 (3.5)

5.4 (4.1)

Twin births (pairs)

4 (5.3%)

6 (7.7%)

Infant baseline FT4 (pmol/L)

12.2 (6.9)

10.5 (6.3)

Infant baseline leg length (mm)

38.7 (7.1)

39.54 (6.8)

Maternal age (years)

28.8 (5.8)

28.9 (5.8)

Maternal history of smoking during pregnancy

16 (22%)

20 (26%)

Maternal history of alcohol during pregnancy

6 (8%)

4 (5%)

Maternal FT4 (pmol/L)

16.5 (3.2)

15.9 (2.5)

Premature rupture of membrane

30 (40.5%)

24 (30.8%)

Evidence of recent maternal infectiona

21 (28.0%)

19 (24.4%)

Antenatal steroid therapy

72 (96.0%)

73 (93.6%)

Delivery by Caesarean section

24 (32.0%)

27 (35.1%)

  1. Data expressed as mean (SD) for continuous outcomes, x (%) for categorical outcomes.
  2. aMaternal infection was defined as maternal pyrexia >38°C or raised maternal blood C-reactive protein concentration during week before birth.