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Table 3 Recruitment in trials

From: A reinvestigation of recruitment to randomised, controlled, multicenter trials: a review of trials funded by two UK funding agencies

 

1994 to 2002

2002 to 2008

Total

Total

P value

With CTU

Without CTU

P value

 

N

n (%)

N

n (%)

N

n (%)

N

n (%)

 

Was recruitment a success?

122

 

73

 

0.002a

31

 

40

 

0.235a

Yes

 

38 (31)

 

40 (55)

 

20 (65)

 

19 (48)

No

 

84 (69)

 

33 (45)

 

11 (36)

 

21 (53)

Was the recruitment target revised?

122

 

73

 

0.036a

31

 

40

 

0.1183a

Yes

 

42 (34)

 

14 (19)

 

3 (10)

 

11 (28)

No

 

76 (62)

 

56 (77)

 

27 (87)

 

28 (70)

Missing

 

4 (3)

 

3 (4)

 

1 (3)

 

1 (3)

Final recruitment figure

          

Original target:

122

 

73

 

<0.001b

31

 

40

 

<0.001b

≥100%

 

38 (31)

 

40 (55)

 

20 (65)

 

19 (48)

≥80% but <100%

 

29 (24)

 

17 (23)

 

8 (26)

 

9 (23)

<80%

 

55 (45)

 

16 (22)

 

3 (10)

 

12 (30)

Revised target:

42

 

14

 

0.021b

3

 

11

 

N/Ab

≥100%

 

19 (45)

 

10 (71)

 

2 (67)

 

8 (73)

≥80% but <100%

 

15 (36)

 

3 (21)

 

0 (0)

 

3 (27)

<80%

 

8 (19)

 

1 (7)

  

1 (33)

 

0 (0)

 
  1. a P values calculated using χ 2 tests, excluding missing categories.
  2. b P values calculated using χ 2 tests for trend; in the final case counts were too small to perform tests.
  3. CTU, clinical trials unit; N/A, not applicable.