From: Investigator experiences with financial conflicts of interest in clinical trials
Characteristics | Respondents (N = 732) |
---|---|
 | n (%) |
Primary appointment | Â |
   University or academic teaching hospital | 684(93) |
   Non-academic community-based hospital | 27(4) |
   Other (e.g. private practice, cancer centre, pharmaceutical) | 21(3) |
Type of clinical trial | Â |
   Non-industry trials only | 240(33) |
   Industry trials only | 54(7) |
   Both non-industry and industry trials | 406(55) |
   None | 28(4) |
   Did not answer | 4(1) |
Number of years of experience in clinical trials | Â |
   ≤ 5 | 192(26) |
   > 5 | 489(67) |
   Not applicable | 28(4) |
   Did not answer | 23(3) |
Most senior role in clinical trial | Â |
   Principal investigator for entire trial -(trial PI) | 466(64) |
   Principal investigator for site, No overall PI experience- (site PI) | 177(24) |
   Other (No PI or site-PI experience) | 56(8) |
   Did not answer | 33(5) |
Intervention(s) studied * | Â |
   Drug therapy | 552(75) |
   Device/equipment | 217(30) |
   Diagnostic tests | 174(24) |
   Surgery/procedure | 151(21) |
   Education/counselling | 139(19) |
   Management policy (e.g. specific thresholds for transfusion) | 89(12) |
   Complementary and alternative medicine | 78(11) |
   Psychotherapy | 37(5) |
   Other (e.g. exercise, nutrition, radiation) | 113(15) |
Trial sites | Â |
   Single | 94(13) |
   Multiple | 252(34) |
   Both (single and multiple) | 353(48) |
   Did not answer | 33(5) |
Conflict of interest exposure | Â |
   Any | 269(37) |
Personal only | 33(5) |
Witness of colleague | 184(25) |
Both personal and witness of colleague | 52(7) |
   None | 402(55) |
   Did not answer | 61(8) |