Table 2 Association Between Characteristics of the Included Randomised Controlled Trials and the Type of Intention-to-treat Reporting
Type of Intention-to-treat | Journal Medical vs. specialty | Placebo Non-placebo vs. placebo | Post-randomization exclusion Reported vs. not reported | Flow chart Not reported vs. reported | Sample size calculation Not reported vs. reported | Lost to follow-up Not reported vs. reported | Sequence Generation Not adequate vs. adequate | Allocation concealment Not adequate vs. adequate | Blinding Not adequate vs. adequate |
|---|---|---|---|---|---|---|---|---|---|
| Â | Unadjusted Odds Ratio (Confidence Interval 95%) | ||||||||
mITT | 1.16 (0.63 to 2.12) | 2.67 (1.44 to 4.92) | 2.62 (1.41 to 4.88) | 1.17 (0.62 to 2.20) | 1.87 (0.87 to 4.02) | 1.09 (0.59 to 2.01) | 1.42 (1.05 to 1.93) | 1.01 (0.74 to 1.36) | 0.50 (0.27 to 0.93) |
"no ITT" | 2.64 (1.64 to 4.25) | 1.87 (1.14 to 3.05) | 1.30 (0.82 to 2.06) | 3.14 (1.94 to 5.07) | 4.47 (2.55 to 7.88) | 2.41 (1.50 to 3.86) | 1.52 (1.23 to 1.98) | 1.53 (1.17 to 1.99) | 1.25 (0.74 to 2.12) |
| Â | Adjusted Odds Ratio (Confidence Interval 95%) | ||||||||
mITT | 1.43 (0.61 to 3.35) | 2.85 (1.22 to 6.63) | 3.43 (1.70 to 6.95) | 1.05 (0.47 to 2.37) | 3.24 (1.32 to 7.98) | 1.13 (0.54 to 2.36) | 1.15 (0.79 to 1.69) | 0.98 (0.69 to 1.41) | 1.00 (0.43 to 2.34) |
"no ITT" | 1.87 (0.94 to 3.69) | 4.11 (2.02 to 8.36) | 2.27 (1.30 to 3.93) | 1.92 (1.03 to 3.55) | 4.05 (2.10 to 7.84) | 2.09 (1.20 to 3.66) | 1.06 (0.79 to 1.43) | 1.24 (0.91 to 1.69) | 1.88 (0.90 to 3.94) |