Topic | Issues covered* |
---|---|
Issues in RCTs | • Biases resulting from patient withdrawal in RCTs and how to address them; |
 | • Design and analysis issues in knowledge translation trials in primary care; |
 | • Testing for blinding at the end of an RCT [5]; |
 | • Prognostic imbalance in RCTs; |
 | • Dynamic allocation methods: why the controversy? |
 | • Statistical issues in the use of composite outcomes clinical trials. |
Issues in cluster RCTs | • Clustered measurement in cluster randomized trials; |
 | • Imputation strategies for missing binary outcomes in cluster randomized trials. |
Non-inferiority designs | • What's wrong with non-inferiority designs? |
Pragmatic Trials | • A pragmatic-explanatory continuum summary (PRECIS) [6]; |
Meta-analysis issues | • Empirical priors for between-study heterogeneity in meta-analysis; |
 | • Precision in meta-analysis; |
 | • Indirect comparisons for evaluating healthcare interventions [7]. |
Other issues | • Bias in logistic regression due to omitted covariates; |
 | • Statistical genetics and coronary artery disease; |
 | • Longitudinal modeling when the response and time-dependent covariates are measured at distinct time-points. |