Withdrawal Criteria |
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Pregnancy |
Hypophosphataemia (serum PO4 <0.8 mmol/L despite dose reduction of treatment/placebo) |
Hyperphosphataemia (serum PO4 >1.8 mmol/L in subjects receiving placebo) |
Occurrence of any serious adverse event, intercurrent illness or laboratory abnormality which, in the opinion of the investigators, warrants the subject's permanent withdrawal from the study |
Poor compliance with study medication |
Poor attendance at study visits |
Subject inability to tolerate study medication due to side effect profile |
Subject decision to withdraw |
Deteriorating renal function |
Subject lost to follow-up (loss of contact before final study visit) |