Table 5 Early death, late death or PD by treatment
From: Pre-referral rectal artesunate in severe malaria: flawed trial
Non-ITT Analysis | ||||
|---|---|---|---|---|
Status | Artesunate | Placebo | RD | p -value* |
Death ≤ 6 hours | 56 | 51 | -0.001 | 1.00 |
Death > 6 hours | 98 | 126 | 0.005 | 0.14 |
Alive with PD | 2 | 13 | 0.002 | 0.01 |
Alive and No PD | 5916 | 5806 | -0.006 | - |
Total | 6072 | 5996 |  | 0.01†|
ITT Analysis | ||||
Status | Artesunate | Placebo | RD | p -value* |
Death ≤ 6 hours | 86 | 85 | 0.000 | 1.00 |
Death > 6 hours | 172 | 203 | 0.004 | 0.26 |
Alive with PD | 15 | 22 | 0.001 | 0.70 |
Alive and No PD | 8681 | 8562 | -0.004 | - |
Total | 8954 | 8872 |  | 0.23†|